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  • CCS Authors Team

Unexpected role of STAT3 as tumor suppressor in lung cancer


"The study identifies the STAT3 oncogene as potent tumor suppressor in lung cancer patients with a smoking history. This unexpected result has significant therapeutic implications as drugs inhibiting JAK/STAT3 in lung cancer are currently in development. The clinical use of such inhibitors thus needs to be very carefully evaluated", CCS co-authors Wolfgang Gruber, Fritz Aberger and Lukas Kenner say.

see press article in derstandard and original article published in Nature Communications


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Cancer Cluster Salzburg at SCRI

3rd Medical Department

Paracelsus Medical University Clinics Salzburg

Müllner Hauptstrasse 48, 5020 Salzburg, Austria

Email: ccs@sbg.ac.at

Cancer Cluster Salzburg at PLUS

Department of Biosciences

University of Salzburg

Hellbrunner Strasse 34, 5020 Salzburg, Austria

Email: ccs@sbg.ac.at