CCS Publications  2020

  • Winter P, Stubenvoll S, Scheiblhofer S, Joubert IA, Strasser L, Briganser C, Soh WT, Hofer F, Kamenik AS, Dietrich V, Michelini S, Laimer J, Lackner P, Horejs-Hoeck J, Tollinger M, Liedl KR, Brandstetter J, Huber CG, Weiss R: In silico Design of Phl p 6 Variants With Altered Fold-Stability Significantly Impacts Antigen Processing, Immunogenicity and Immune Polarization. Front Immunol 2020, 11:1824.

  • Westmeier D, Posselt G, Hahlbrock A, Bartfeld S, Vallet C, Abfalter C, Docter D, Knauer SK, Wessler S, Stauber RH: Correction: Nanoparticle binding attenuates the pathobiology of gastric cancer-associated Helicobacter pylori. Nanoscale 2020, 12:2154-2155.

  • Wang Y, Gorlova OY, Gorlov IP, Zhu M, Dai J, Albanes D, Lam S, Tardon A, Chen C, Goodman GE, Bojesen SE, Landi MT, Johansson M, Risch A, Wichmann HE, Bickeboller H, Christiani DC, Rennert G, Arnold SM, Brennan P, Field JK, Shete S, Le Marchand L, Melander O, Brunnstrom H, Liu G, Hung RJ, Andrew AS, Kiemeney LA, Zienolddiny S, Grankvist K, Johansson M, Caporaso NE, Woll PJ, Lazarus P, Schabath MB, Aldrich MC, Stevens VL, Ma H, Jin G, Hu Z, Amos CI, Shen H: Association Analysis of Driver Gene-Related Genetic Variants Identified Novel Lung Cancer Susceptibility Loci with 20,871 Lung Cancer Cases and 15,971 Controls. Cancer Epidemiol Biomarkers Prev 2020, 29:1423-1429.

  • Wagner SM, Melchardt T, Greil R: Ropeginterferon alfa-2b for the treatment of patients with polycythemia vera. Drugs Today (Barc) 2020, 56:195-202.

  • Wagner SM, Melchardt T, Egle A, Magnes T, Skrabs C, Staber P, Simonitsch-Klupp I, Panny M, Lehner B, Greil R, Keil F, Jager U, Sillaber C: Treatment with brentuximab vedotin plus bendamustine in unselected patients with CD30-positive aggressive lymphomas. Eur J Haematol 2020, 104:251-258.

  • Tedeschi A, Greil R, Demirkan F, Robak T, Moreno C, Barr PM, Anz B, Simpson D, Gaidano G, Bairey O, Stevens D, Gill D, Flinn IW, Kipps TJ, Burger JA, Lin J, Webb T, Fedorov V, Styles L, Gribben JG: A cross-trial comparison of single-agent ibrutinib versus chlorambucil-obinutuzumab in previously untreated patients with chronic lymphocytic leukemia or small lymphocytic lymphoma. Haematologica 2020, 105:e164-e168.

  • Szenes E, Harzschel A, Decker S, Tissino E, Pischeli J, Gutjahr JC, Kissel S, Pennisi S, Hopner JP, Egle A, Zaborsky N, Dierks C, Follo M, Chigaev A, Zucchetto A, Greil R, Gattei V, Hartmann TN: TCL1 transgenic mice as a model for CD49d-high chronic lymphocytic leukemia. Leukemia 2020, 34:2498-2502.

  • Subbiah V, Lassen U, Elez E, Italiano A, Curigliano G, Javle M, de Braud F, Prager GW, Greil R, Stein A, Fasolo A, Schellens JHM, Wen PY, Viele K, Boran AD, Gasal E, Burgess P, Ilankumaran P, Wainberg ZA: Dabrafenib plus trametinib in patients with BRAF(V600E)-mutated biliary tract cancer (ROAR): a phase 2, open-label, single-arm, multicentre basket trial. Lancet Oncol 2020, 21:1234-1243.

  • Soh WT, Demir F, Dall E, Perrar A, Dahms SO, Kuppusamy M, Brandstetter H, Huesgen PF: ExteNDing Proteome Coverage with Legumain as a Highly Specific Digestion Protease. Anal Chem 2020, 92:2961-2971.

  • Singer CF, Pfeiler G, Hubalek M, Bartsch R, Stoger H, Pichler A, Petru E, Bjelic-Radisic V, Greil R, Rudas M, Maria Tea MK, Wette V, Petzer AL, Sevelda P, Egle D, Dubsky PC, Filipits M, Fitzal F, Exner R, Jakesz R, Balic M, Tinchon C, Bago-Horvath Z, Frantal S, Gnant M, Austrian B, Colorectal Cancer Study G: Efficacy and safety of the therapeutic cancer vaccine tecemotide (L-BLP25) in early breast cancer: Results from a prospective, randomised, neoadjuvant phase II study (ABCSG 34). Eur J Cancer 2020, 132:43-52.

  • Schneider CV, Hamesch K, Gross A, Mandorfer M, Moeller LS, Pereira V, Pons M, Kuca P, Reichert MC, Benini F, Burbaum B, Voss J, Gutberlet M, Woditsch V, Lindhauer C, Fromme M, Kumpers J, Bewersdorf L, Schaefer B, Eslam M, Bals R, Janciauskiene S, Carvao J, Neureiter D, Zhou B, Woran K, Bantel H, Geier A, Dirrichs T, Stickel F, Teumer A, Verbeek J, Nevens F, Govaere O, Krawczyk M, Roskams T, Haybaeck J, Lurje G, Chorostowska-Wynimko J, Genesca J, Reiberger T, Lammert F, Krag A, George J, Anstee QM, Trauner M, Datz C, Gaisa NT, Denk H, Trautwein C, Aigner E, Strnad P, European Alpha-1 Liver Study G: Liver Phenotypes of European Adults Heterozygous or Homozygous for Pi *Z Variant of AAT (Pi *MZ vs Pi *ZZ genotype) and Noncarriers. Gastroenterology 2020, 159:534-548 e511.

  • Schlick K, Hohla F, Hamacher F, Hackl H, Hufnagl C, Markus S, Magnes T, Gampenrieder SP, Melchardt T, Stattner S, Hauser-Kronberger C, Greil R, Rinnerthaler G: Overcoming negative predictions of microRNA expressions to gemcitabine response with FOLFIRINOX in advanced pancreatic cancer patients. Future Sci OA 2020, 7:FSO644.

  • Schlenk RF, Paschka P, Krzykalla J, Weber D, Kapp-Schwoerer S, Gaidzik VI, Leis C, Fiedler W, Kindler T, Schroeder T, Mayer K, Lubbert M, Wattad M, Gotze K, Horst HA, Koller E, Wulf G, Schleicher J, Bentz M, Greil R, Hertenstein B, Krauter J, Martens U, Nachbaur D, Abu Samra M, Girschikofsky M, Basara N, Benner A, Thol F, Heuser M, Ganser A, Dohner K, Dohner H: Gemtuzumab Ozogamicin in NPM1-Mutated Acute Myeloid Leukemia: Early Results From the Prospective Randomized AMLSG 09-09 Phase III Study. J Clin Oncol 2020, 38:623-632.

  • Schimanski CC, Kasper S, Hegewisch-Becker S, Schroder J, Overkamp F, Kullmann F, Bechstein WO, Vohringer M, Ollinger R, Lordick F, Heinemann V, Geissler M, Schulz-Abelius A, Bernhard H, Schon MR, Greil R, Galle P, Lang H, Schmidtmann I, Moehler M: Adjuvant MUC vaccination with tecemotide after resection of colorectal liver metastases: a randomized, double-blind, placebo-controlled, multicenter AIO phase II trial (LICC). Oncoimmunology 2020, 9:1806680.

  • Scheidt T, Alka O, Gonczarowska-Jorge H, Gruber W, Rathje F, Dell'Aica M, Rurik M, Kohlbacher O, Zahedi RP, Aberger F, Huber CG: Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells. Cell Commun Signal 2020, 18:99.

  • Schaffler-Schaden D, Sassmann R, Johansson T, Gampenrieder SP, Rinnerthaler G, Lampl K, Herfert J, Lenzhofer C, Landkammer YT, Rieder F, Greil R, Flamm M, Niebauer J: Comparison of high tone therapy and transcutaneous electrical nerve stimulation therapy in chemotherapy-induced polyneuropathy. Medicine (Baltimore) 2020, 99:e20149.

  • Sarajlic M, Neuper T, Vetter J, Schaller S, Klicznik MM, Gratz IK, Wessler S, Posselt G, Horejs-Hoeck J: H. pylori modulates DC functions via T4SS/TNFalpha/p38-dependent SOCS3 expression. Cell Commun Signal 2020, 18:160.

  • Samonig L, Loipetzberger A, Blochl C, Rurik M, Kohlbacher O, Aberger F, Huber CG: Proteins and Molecular Pathways Relevant for the Malignant Properties of Tumor-Initiating Pancreatic Cancer Cells. Cells 2020, 9.

  • Samadi N, Klems M, Heiden D, Bauer R, Kitzmuller C, Weidmann E, Ret D, Ondracek AS, Duschl A, Horejs-Hoeck J, Untersmayr E: Nitrated food proteins induce a regulatory immune response associated with allergy prevention after oral exposure in a Balb/c mouse food allergy model. Allergy 2020, 75:412-422.

  • Rinnerthaler G, Gampenrieder SP, Hackl H, Steiner M, Monzo-Fuentes C, Melchardt T, Magnes T, Huemer F, Westphal T, Hufnagl C, Hauser-Kronberger C, Egle A, Greil R: Low Expression of miR-20a-5p Predicts Benefit to Bevacizumab in Metastatic Breast Cancer Patients Treated within the TANIA Phase III Trial. J Clin Med 2020, 9.

  • Riedl JM, Posch F, Prager G, Eisterer W, Oehler L, Sliwa T, Wilthoner K, Petzer A, Pichler P, Hubmann E, Winder T, Burgstaller S, Korger M, Andel J, Greil R, Neumann HJ, Pecherstorfer M, Philipp-Abbrederis K, Djanani A, Gruenberger B, Laengle F, Woll E, Gerger A: The AST/ALT (De Ritis) ratio predicts clinical outcome in patients with pancreatic cancer treated with first-line nab-paclitaxel and gemcitabine: post hoc analysis of an Austrian multicenter, noninterventional study. Ther Adv Med Oncol 2020, 12:1758835919900872.

  • Reinders J, Altenbuchinger M, Limm K, Schwarzfischer P, Scheidt T, Strasser L, Richter J, Szczepanowski M, Huber CG, Klapper W, Spang R, Oefner PJ: Platform independent protein-based cell-of-origin subtyping of diffuse large B-cell lymphoma in formalin-fixed paraffin-embedded tissue. Sci Rep 2020, 10:7876.

  • Prutsch N, Gurnhofer E, Suske T, Liang HC, Schlederer M, Roos S, Wu LC, Simonitsch-Klupp I, Alvarez-Hernandez A, Kornauth C, Leone DA, Svinka J, Eferl R, Limberger T, Aufinger A, Shirsath N, Wolf P, Hielscher T, Sternberg C, Aberger F, Schmoellerl J, Stoiber D, Strobl B, Jager U, Staber PB, Grebien F, Moriggl R, Muller M, Inghirami GG, Sanda T, Look AT, Turner SD, Kenner L, Merkel O: Correction: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma. Leukemia 2020, 34:3105.

  • Primavesi F, Andreasi V, Hoogwater FJH, Partelli S, Wiese D, Heidsma C, Cardini B, Klieser E, Marsoner K, Froschl U, Thalhammer S, Fischer I, Gobel G, Hauer A, Kiesslich T, Ellmerer P, Klug R, Neureiter D, Wundsam H, Sellner F, Kornprat P, Fugger R, Ofner D, Nieveen van Dijkum EJM, Bartsch DK, de Kleine RHJ, Falconi M, Stattner S: A Preoperative Clinical Risk Score Including C-Reactive Protein Predicts Histological Tumor Characteristics and Patient Survival after Surgery for Sporadic Non-Functional Pancreatic Neuroendocrine Neoplasms: An International Multicenter Cohort Study. Cancers (Basel) 2020, 12.

  • Posch A, Hofer-Zeni S, Klieser E, Primavesi F, Naderlinger E, Brandstetter A, Filipits M, Urbas R, Swiercynski S, Jager T, Winkelmann P, Kiesslich T, Lu L, Neureiter D, Stattner S, Holzmann K: Hot Spot TERT Promoter Mutations Are Rare in Sporadic Pancreatic Neuroendocrine Neoplasms and Associated with Telomere Length and Epigenetic Expression Patterns. Cancers (Basel) 2020, 12.

  • Pinsino A, Bastus NG, Busquets-Fite M, Canesi L, Cesaroni P, Drobne D, Duschl A, Ewart MA, Gispert I, Horejs-Hoeck J, Italiani P, Kemmerling B, Kille P, Prochazkova P, Puntes VF, Spurgeon DJ, Svendsen C, Wilde CJ, Boraschi D: Probing the immune responses to nanoparticles across environmental species. A perspective of the EU Horizon 2020 project PANDORA. Environmental Science-Nano 2020, 7:3216-3232.

  • Pinheiro DF, Szenes-Nagy AB, Maurano MM, Lietzenmayer M, Klicznik MM, Holly R, Kirchmeier D, Kitzmueller S, Achatz-Straussberger G, Rosenblum MD, Thalhamer J, Abbas AK, Gratz IK: Cutting Edge: Tissue Antigen Expression Levels Fine-Tune T Cell Differentiation Decisions In Vivo. J Immunol 2020, 205:2577-2582.

  • Petzer AL, Sperr WR, Buxhofer-Ausch V, Sliwa T, Schmidt S, Greil R, Wolfler A, Pichler P, Dormann C, Burgstaller S, Tinchon C, Lang A, Goebel F, Uthman S, Muenchmeier N, Valent P: A multicenter retrospective evaluation of Chronic Myeloid Leukemia (CML) therapy in Austria assessing the impact of early treatment response on patient outcomes in a real-life setting : R-EFECT study. Wien Klin Wochenschr 2020, 132:415-422.

  • Paul K, Bottinger K, Mitic BM, Scherfler G, Posch C, Behrens D, Huber CG, Herwig C: Development, characterization, and application of a 2-Compartment system to investigate the impact of pH inhomogeneities in large-scale CHO-based processes. Eng Life Sci 2020, 20:368-378.

  • Park E, Chen J, Moore A, Mangolini M, Santoro A, Boyd JR, Schjerven H, Ecker V, Buchner M, Williamson JC, Lehner PJ, Gasparoli L, Williams O, Bloehdorn J, Stilgenbauer S, Leitges M, Egle A, Schmidt-Supprian M, Frietze S, Ringshausen I: Stromal cell protein kinase C-beta inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance. Sci Transl Med 2020, 12.

  • Papakonstantinou A, Matikas A, Bengtsson NO, Malmstrom P, Hedayati E, Steger G, Untch M, Hubbert L, Johansson H, Hellstrom M, Gnant M, Loibl S, Greil R, Moebus V, Foukakis T, Bergh J: Efficacy and safety of tailored and dose-dense adjuvant chemotherapy and trastuzumab for resected HER2-positive breast cancer: Results from the phase 3 PANTHER trial. Cancer 2020, 126:1175-1182.

  • Papakonstantinou A, Hedayati E, Hellstrom M, Johansson H, Gnant M, Steger G, Greil R, Untch M, Moebus V, Loibl S, Foukakis T, Bergh J, Matikas A: Neutropenic complications in the PANTHER phase III study of adjuvant tailored dose-dense chemotherapy in early breast cancer. Acta Oncol 2020, 59:75-81.

  • Ozsoy M, Zimmermann FA, Feichtinger RG, Mayr JA, Kofler B, Neureiter D, Klieser E, Schutz S, Weghuber D, Schneider AM: Changes in the expression of oxidative phosphorylation complexes in the aging intestinal mucosa. Exp Gerontol 2020, 135:110924.

  • Oberhuber M, Pecoraro M, Rusz M, Oberhuber G, Wieselberg M, Haslinger P, Gurnhofer E, Schlederer M, Limberger T, Lagger S, Pencik J, Kodajova P, Hogler S, Stockmaier G, Grund-Groschke S, Aberger F, Bolis M, Theurillat JP, Wiebringhaus R, Weiss T, Haitel A, Brehme M, Wadsak W, Griss J, Mohr T, Hofer A, Jager A, Pollheimer J, Egger G, Koellensperger G, Mann M, Hantusch B, Kenner L: STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer. Mol Syst Biol 2020, 16:e9247.

  • Neureiter D, Mayr C, Winkelmann P, Neumayer B, Klieser E, Wagner A, Hufnagl C, Emmanuel K, Holzinger J, Koch O, Kiesslich T, Varga M: Expression of the microRNA-200 Family, microRNA-205, and Markers of Epithelial-Mesenchymal Transition as Predictors for Endoscopic Submucosal Dissection over Esophagectomy in Esophageal Adenocarcinoma: A Single-Center Experience. Cells 2020, 9.

  • Neureiter D, Mayr C, Kiesslich T: How do we choose the appropriate chemotherapeutic agents for biliary tract cancer? Expert Opin Pharmacother 2020, 21:243-245.

  • Neuper T, Frauenlob T, Sarajlic M, Posselt G, Wessler S, Horejs-Hoeck J: TLR2, TLR4 and TLR10 Shape the Cytokine and Chemokine Release of H. pylori-Infected Human DCs. Int J Mol Sci 2020, 21.

  • Murthy RK, Loi S, Okines A, Paplomata E, Hamilton E, Hurvitz SA, Lin NU, Borges V, Abramson V, Anders C, Bedard PL, Oliveira M, Jakobsen E, Bachelot T, Shachar SS, Muller V, Braga S, Duhoux FP, Greil R, Cameron D, Carey LA, Curigliano G, Gelmon K, Hortobagyi G, Krop I, Loibl S, Pegram M, Slamon D, Palanca-Wessels MC, Walker L, Feng W, Winer EP: Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer. N Engl J Med 2020, 382:597-609.

  • Muller AT, Posselt G, Gabernet G, Neuhaus C, Bachler S, Blatter M, Pfeiffer B, Hiss JA, Dittrich PS, Altmann KH, Wessler S, Schneider G: Morphing of Amphipathic Helices to Explore the Activity and Selectivity of Membranolytic Antimicrobial Peptides. Biochemistry 2020, 59:3772-3781.

  • Ludwig H, Ponisch W, Knop S, Egle A, Hinke A, Schreder M, Lechner D, Hajek R, Gunsilius E, Petzer A, Weisel K, Niederwieser D, Einsele H, Willenbacher W, Rumpold H, Pour L, Jelinek T, Krenosz KJ, Meckl A, Nolte S, Melchardt T, Greil R, Zojer N: Quality of life in patients with relapsed/refractory multiple myeloma during ixazomib-thalidomide-dexamethasone induction and ixazomib maintenance therapy and comparison to the general population. Leuk Lymphoma 2020, 61:377-386.

  • Leisch M, Greil R, Pleyer L: IDO in MDS/AML disease progression and its role in resistance to azacitidine: a potential new drug target? Br J Haematol 2020, 190:314-317.

  • Leeksma AC, Derks IAM, Kasem MH, Kilic E, de Klein A, Jager MJ, van de Loosdrecht AA, Jansen JH, Navrkalova V, Faber LM, Zaborsky N, Egle A, Zenz T, Pospisilova S, Abdel-Wahab O, Kater AP, Eldering E: The Effect of SF3B1 Mutation on the DNA Damage Response and Nonsense-Mediated mRNA Decay in Cancer. Front Oncol 2020, 10:609409.

  • Korotchenko E, Moya R, Scheiblhofer S, Joubert IA, Horejs-Hoeck J, Hauser M, Calzada D, Iraola V, Carnes J, Weiss R: Laser-facilitated epicutaneous immunotherapy with depigmented house dust mite extract alleviates allergic responses in a mouse model of allergic lung inflammation. Allergy 2020, 75:1217-1228.

  • Kohlberger M, Wildner S, Regl C, Huber CG, Gadermaier G: Rituximab-specific DNA aptamers are able to selectively recognize heat-treated antibodies. PLoS One 2020, 15:e0241560.

  • Klicznik MM, Benedetti A, Gail LM, Varkhande SR, Holly R, Laimer M, Stoecklinger A, Sir A, Reitsamer R, Neuper T, Horejs-Hoeck J, Rosenblum MD, Campbell DJ, Murauer EM, Gratz IK: A novel humanized mouse model to study the function of human cutaneous memory T cells in vivo in human skin. Sci Rep 2020, 10:11164.

  • Kim-Wanner SZ, Assenov Y, Nair MB, Weichenhan D, Benner A, Becker N, Landwehr K, Kuner R, Sultmann H, Esteller M, Koch I, Lindner M, Meister M, Thomas M, Bieg M, Klingmuller U, Schlesner M, Warth A, Brors B, Seifried E, Bonig H, Plass C, Risch A, Muley T: Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenocarcinoma Reveals Predictive Aberrant Methylation in the Promoter Region of the Long Noncoding RNA PLUT: An Exploratory Study. J Thorac Oncol 2020, 15:1338-1350.

  • Joubert AI, Geppert M, Johnson L, Mills-Goodlet R, Michelini S, Korotchenko E, Duschl A, Weiss R, Horejs-Hock J, Himly M: Mechanisms of Particles in Sensitization, Effector Function and Therapy of Allergic Disease. Front Immunol 2020, 11:1334.

  • Ji X, Mukherjee S, Landi MT, Bosse Y, Joubert P, Zhu D, Gorlov I, Xiao X, Han Y, Gorlova O, Hung RJ, Brhane Y, Carreras-Torres R, Christiani DC, Caporaso N, Johansson M, Liu G, Bojesen SE, Le Marchand L, Albanes D, Bickeboller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Chen C, Byun J, Dragnev KH, Field JK, Kiemeney LF, Lazarus P, Zienolddiny S, Lam S, Schabath MB, Andrew AS, Bertazzi PA, Pesatori AC, Diao N, Su L, Song L, Zhang R, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman C, Wilkens L, Fernandez-Somoano A, Fernandez-Tardon G, Heijden E, Kim JH, Davies MPA, Marcus MW, Brunnstrom H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Goodman GE, Cox A, Taylor F, Woll P, Wichmann E, Muley T, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd F, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Butler LM, Offit K, Srinivasan P, Bandlamudi C, Hellmann MD, Solit DB, Robson ME, Rudin CM, Stadler ZK, Taylor BS, Berger MF, Houlston R, McLaughlin J, Stevens V, Nickle DC, Obeidat M, Timens W, Artigas MS, Shete S, Brenner H, Chanock S, Brennan P, McKay JD, Amos CI: Protein-altering germline mutations implicate novel genes related to lung cancer development. Nat Commun 2020, 11:2220.

  • Jarzab M, Posselt G, Meisner-Kober N, Wessler S: Helicobacter pylori-Derived Outer Membrane Vesicles (OMVs): Role in Bacterial Pathogenesis? Microorganisms 2020, 8.

  • Hufnagl C, Leisch M, Weiss L, Melchardt T, Moik M, Asslaber D, Roland G, Steininger P, Meissnitzer T, Neureiter D, Greil R, Egle A: Evaluation of circulating cell-free DNA as a molecular monitoring tool in patients with metastatic cancer. Oncol Lett 2020, 19:1551-1558.

  • Huemer F, Weiss L, Regitnig P, Winder T, Hartmann B, Thaler J, Piringer G, Schmitt CA, Eisterer W, Ganzer H, Wustner A, Andel J, Jagdt B, Ulmer H, Greil R, Woll E: Local and Central Evaluation of HER2 Positivity and Clinical Outcome in Advanced Gastric and Gastroesophageal Cancer-Results from the AGMT GASTRIC-5 Registry. J Clin Med 2020, 9.

  • Huemer F, Piringer G, Schlintl V, Hackl H, Rinnerthaler G, Thaler J, Greil R, Weiss L: Hospitalizations and Clinical Outcome in Metastatic Colorectal Cancer During Regorafenib or TAS-102 Therapy. Cancers (Basel) 2020, 12.

  • Huemer F, Leisch M, Geisberger R, Melchardt T, Rinnerthaler G, Zaborsky N, Greil R: Combination Strategies for Immune-Checkpoint Blockade and Response Prediction by Artificial Intelligence. Int J Mol Sci 2020, 21.

  • Huemer F, Klieser E, Neureiter D, Schlintl V, Rinnerthaler G, Pages F, Kirilovsky A, El Sissy C, Iglseder W, Singhartinger F, Jager T, Dinnewitzer A, Zaborsky N, Steiner M, Greil R, Weiss L: Impact of PD-L1 Scores and Changes on Clinical Outcome in Rectal Cancer Patients Undergoing Neoadjuvant Chemoradiotherapy. J Clin Med 2020, 9.

  • Hollbacher B, Duhen T, Motley S, Klicznik MM, Gratz IK, Campbell DJ: Transcriptomic Profiling of Human Effector and Regulatory T Cell Subsets Identifies Predictive Population Signatures. Immunohorizons 2020, 4:585-596.

  • Hinterholzer A, Stanojlovic V, Regl C, Huber CG, Cabrele C, Schubert M: Identification and Quantification of Oxidation Products in Full-Length Biotherapeutic Antibodies by NMR Spectroscopy. Anal Chem 2020, 92:9666-9673.

  • Himly M, Geppert M, Hofer S, Hofstatter N, Horejs-Hock J, Duschl A: When Would Immunologists Consider a Nanomaterial to be Safe? Recommendations for Planning Studies on Nanosafety. Small 2020, 16:e1907483.

  • Heimesaat MM, Schmidt AM, Mousavi S, Escher U, Tegtmeyer N, Wessler S, Gadermaier G, Briza P, Hofreuter D, Bereswill S, Backert S: Peptidase PepP is a novel virulence factor of Campylobacter jejuni contributing to murine campylobacteriosis. Gut Microbes 2020, 12:1770017.

  • Heibl S, Buxhofer-Ausch V, Schmidt S, Webersinke G, Lion T, Piringer G, Kuehr T, Wolf D, Melchardt T, Greil R, Thaler J: A phase 1 study to evaluate the feasibility and efficacy of the addition of ropeginterferon alpha-2b to imatinib treatment in patients with chronic phase chronic myeloid leukemia (CML) not achieving a deep molecular response (molecular remission 4.5)-AGMT_CML 1. Hematol Oncol 2020, 38:792-798.

  • Gutzeit A, Fischmann A, Forstner R, Goette R, Herzog B, Kurtz C, Hebler C, Ladinger A, Froehlich JM, Blautzik J, Kolokythas O, Matoori S, Kos S, Reischauer C, Schefer H, Dubsky P, Gampenrieder SP, Hergan K, Gaissmaier W, Koh DM, Meissnitzer M: "I was seen by a radiologist, but unfortunately I can't remember the name and I still have questions. What should I do?" Radiologists should give thoughts to improve service professionalism and patient esteem. Cancer Imaging 2020, 20:18.

  • Grund-Groschke S, Ortner D, Szenes-Nagy AB, Zaborsky N, Weiss R, Neureiter D, Wipplinger M, Risch A, Hammerl P, Greil R, Sibilia M, Gratz IK, Stoitzner P, Aberger F: Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity. Mol Oncol 2020, 14:1930-1946.

  • Gratz IK, Campbell DJ: Resident memory T cells show that it is never too late to change your ways. Nat Immunol 2020, 21:359-360.

  • Gassner FJ, Zaborsky N, Feldbacher D, Greil R, Geisberger R: RNA Editing Alters miRNA Function in Chronic Lymphocytic Leukemia. Cancers (Basel) 2020, 12.

  • Gampenrieder SP, Castagnaviz V, Rinnerthaler G, Greil R: Treatment Landscape for Patients with HER2-Positive Metastatic Breast Cancer: A Review on Emerging Treatment Options. Cancer Manag Res 2020, 12:10615-10629.

  • Esser-Skala W, Wohlschlager T, Regl C, Huber CG: A Simple Strategy to Eliminate Hexosylation Bias in the Relative Quantification of N-Glycosylation in Biopharmaceuticals. Angew Chem Int Ed Engl 2020, 59:16225-16232.

  • Esser-Skala W, Segl M, Wohlschlager T, Reisinger V, Holzmann J, Huber CG: Exploring sample preparation and data evaluation strategies for enhanced identification of host cell proteins in drug products of therapeutic antibodies and Fc-fusion proteins. Anal Bioanal Chem 2020, 412:6583-6593.

  • Elmer DP, Strobl V, Stockmaier G, Dang H-H, Wiederstein M, Licha D, Strobl A, Sternberg C, Tesanovic S, Grund-Groeschke S, Gruber W, Wolff F, Moriggl R, Risch A, Reischl R, Huber CG, Horejs-Hoeck J, Aberger F: Oncogenic GLI1 and STAT1/3 activation drives immunosuppressive tryptophan/kynurenine metabolism via synergistic induction of IDO1 in skin cancer cells. bioRxiv 2020:2020.2005.2004.074757.

  • Eckhard U, Blochl C, Jenkins BGL, Mansfield MJ, Huber CG, Doxey AC, Brandstetter H: Identification and characterization of the proteolytic flagellin from the common freshwater bacterium Hylemonella gracilis. Sci Rep 2020, 10:19052.

  • Dubsky PC, Singer CF, Egle D, Wette V, Petru E, Balic M, Pichler A, Greil R, Petzer AL, Bago-Horvath Z, Fesl C, Meek SM, Kronenwett R, Rudas M, Gnant M, Filipits M, Austrian B, Colorectal Cancer Study G: The EndoPredict score predicts response to neoadjuvant chemotherapy and neoendocrine therapy in hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer patients from the ABCSG-34 trial. Eur J Cancer 2020, 134:99-106.

  • Di Muzio M, Wildner S, Huber S, Hauser M, Vejvar E, Auzinger W, Regl C, Laimer J, Zennaro D, Wopfer N, Huber CG, van Ree R, Mari A, Lackner P, Ferreira F, Schubert M, Gadermaier G: Hydrogen/deuterium exchange memory NMR reveals structural epitopes involved in IgE cross-reactivity of allergenic lipid transfer proteins. J Biol Chem 2020, 295:17398-17410.

  • Dai J, Huang M, Amos CI, Hung RJ, Tardon A, Andrew A, Chen C, Christiani DC, Albanes D, Rennert G, Fan J, Goodman G, Liu G, Field JK, Grankvist K, Kiemeney LA, Le Marchand L, Schabath MB, Johansson M, Aldrich MC, Johansson M, Caporaso N, Lazarus P, Lam S, Bojesen SE, Arnold S, Landi MT, Risch A, Wichmann HE, Bickeboller H, Brennan P, Shete S, Melander O, Brunnstrom H, Zienolddiny S, Woll P, Stevens V, Hu Z, Shen H: Genome-wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk. Int J Cancer 2020, 146:2855-2864.

  • Chichirau BE, Scheidt T, Diechler S, Neuper T, Horejs-Hoeck J, Huber CG, Posselt G, Wessler S: Dissecting the Helicobacter pylori-regulated transcriptome of B cells. Pathog Dis 2020, 78.

  • Bosse Y, Li Z, Xia J, Manem V, Carreras-Torres R, Gabriel A, Gaudreault N, Albanes D, Aldrich MC, Andrew A, Arnold S, Bickeboller H, Bojesen SE, Brennan P, Brunnstrom H, Caporaso N, Chen C, Christiani DC, Field JK, Goodman G, Grankvist K, Houlston R, Johansson M, Johansson M, Kiemeney LA, Lam S, Landi MT, Lazarus P, Le Marchand L, Liu G, Melander O, Rennert G, Risch A, Rosenberg SM, Schabath MB, Shete S, Song Z, Stevens VL, Tardon A, Wichmann HE, Woll P, Zienolddiny S, Obeidat M, Timens W, Hung RJ, Joubert P, Amos CI, McKay JD: Transcriptome-wide association study reveals candidate causal genes for lung cancer. Int J Cancer 2020, 146:1862-1878.

  • Boraschi D, Alijagic A, Auguste M, Barbero F, Ferrari E, Hernadi S, Mayall C, Michelini S, Navarro Pacheco NI, Prinelli A, Swart E, Swartzwelter BJ, Bastus NG, Canesi L, Drobne D, Duschl A, Ewart MA, Horejs-Hoeck J, Italiani P, Kemmerling B, Kille P, Prochazkova P, Puntes VF, Spurgeon DJ, Svendsen C, Wilde CJ, Pinsino A: Addressing Nanomaterial Immunosafety by Evaluating Innate Immunity across Living Species. Small 2020, 16:e2000598.

  • Blochl C, Regl C, Huber CG, Winter P, Weiss R, Wohlschlager T: Towards middle-up analysis of polyclonal antibodies: subclass-specific N-glycosylation profiling of murine immunoglobulin G (IgG) by means of HPLC-MS. Sci Rep 2020, 10:18080.

  • Bjelic-Radisic V, Fitzal F, Knauer M, Steger G, Egle D, Greil R, Schrenk P, Balic M, Singer C, Exner R, Soelkner L, Gnant M, Abcsg: Primary surgery versus no surgery in synchronous metastatic breast cancer: patient-reported quality-of-life outcomes of the prospective randomized multicenter ABCSG-28 Posytive Trial. BMC Cancer 2020, 20:392.

  • Bernegger S, Brunner C, Vizovisek M, Fonovic M, Cuciniello G, Giordano F, Stanojlovic V, Jarzab M, Simister P, Feller SM, Obermeyer G, Posselt G, Turk B, Cabrele C, Schneider G, Wessler S: A novel FRET peptide assay reveals efficient Helicobacter pylori HtrA inhibition through zinc and copper binding. Sci Rep 2020, 10:10563.

  • Bekric D, Neureiter D, Ritter M, Jakab M, Gaisberger M, Pichler M, Kiesslich T, Mayr C: Long Non-Coding RNAs in Biliary Tract Cancer-An Up-to-Date Review. J Clin Med 2020, 9.

  • Barraco F, Greil R, Herbrecht R, Schmidt B, Reiter A, Willenbacher W, Raymakers R, Liersch R, Wroclawska M, Pack R, Burock K, Karumanchi D, Gisslinger H: Real-world non-interventional long-term post-authorisation safety study of ruxolitinib in myelofibrosis. Br J Haematol 2020, 191:764-774.

  • Bago-Horvath Z, Rudas M, Singer CF, Greil R, Balic M, Lax SF, Kwasny W, Hulla W, Gnant M, Filipits M: Predictive Value of Molecular Subtypes in Premenopausal Women with Hormone Receptor-positive Early Breast Cancer: Results from the ABCSG Trial 5. Clin Cancer Res 2020, 26:5682-5688.